Background: Islamic instructions suggest waking up near dawn at night and spending time praying to Allah. This is the time of maximum MELATONIN secretion, that is a hormone mainly functioning in the circadian rhythm. MELATONIN secretion declines with age and leads to different clinical consequences. This study aimed to investigate the MELATONIN levels among night vigil prayers, non-prayer late sleepers, and those with regular night sleep.Methods: A questionnaire including information about age, gender, education, and occupation was used to collect the demographic information of the participants. MELATONIN was measured with two blood draws (at 23:00 to 24:00 and 9:00 to 10:00 a.m.). Results: There was a significant difference between both nocturnal and daily MELATONIN of the night vigil prayers with the other two groups. The average daily MELATONIN serum level had no significant difference in groups of regular night sleepers and the nonpraying late sleepers (p=0.306). Moreover, an adverse significant relationship was found between age and nocturnal MELATONIN (R=0.38, P<0.0001) and between age and daily MELATONIN (R=0.25, P=0.02).Conclusion: The night vigil prayers have a higher average of nocturnal and daily MELATONIN serum secretion compared to the nonpraying late sleepers and regular night sleepers. Therefore, waking up at night accompanied by approaching Allah, prayer, supplication, and good thinking is related to the release of more MELATONIN.

Background: MELATONIN is a hormone secreted by the pineal gland in the brain. It helps regulate other hormones and maintains the body’s daily rhythm, telling us when to fall asleep and when to wake up. Ever since we developed electricity and the lightbulb, we have been decreasing our body’s secretions of MELATONIN by being exposed to bright light after it is dark. Jet lag, shift work and poor vision also affect regular MELATONIN levels. In Chinese Medicine, MELATONIN could be likened to the functions of healthy Liver energy. MELATONIN also helps control the timing and release of female reproductive hormones. It helps determine when a woman starts to menstruate, the frequency and duration of menstrual cycles, and when a woman stops menstruating (menopause).Materials and Methods: This is review article.Results: MELATONIN intake also improved pregnancy rates, which were 19.6 percent among women taking supplements compared with 10.2% for the women not taking any. MELATONIN has strong antioxidant effects.Preliminary evidence suggests that it may help strengthen the immune system. This could have an important effect on male fertility. In anin vitro study involving semen samples taken from 52 men receiving counseling for infertility, semen samples were incubated for 30 minutes with or without 1mm MELATONIN. Positive correlations were found between MELATONIN concentrations and sperm concentration, motility and morphology. Additionally, samples incubated with MELATONIN showed improved percentage of motile and progressively motile cells, and decreased static cells.Conclusion: High endogenous MELATONIN concentrations enhance sperm quality and short-term in vitro exposure to MELATONIN improves aspects of sperm motility.